Penetrating injury of the eye causing bilateral visual loss: An eye opener!

Penetrating injury of the eye.

Penetrating Eye Injury

A 38-year-old man presented to a regional Western Australian hospital after being stabbed in his left eye with a knife. Computerized Tomography (CT) revealed a 7 cm knife blade within the globe extending along the skull base. After transfer to a tertiary hospital, a cerebral angiogram was performed, excluding significant cerebral vascular involvement. Through a multidisciplinary approach with t...

Bilateral Abducent Palsy in Leptospirosis- An Eye Opener to a Rare Neuro Ocular Manifestation: A Case Report

Leptospirosis, a disease of great significance in tropical countries, presents commonly as a biphasic illness with acute febrile episode in the first phase followed by a brief afebrile period and then by the second phase of fever with or without jaundice and renal failure. However, it has varied manifestations and unusual clinical features ascribed to immunological phenomena can occur due to th...

An eye-opener for RNAi therapeutics.

The discovery of the mechanism of RNA interference (RNAi) for knockdown of gene expression has spurred a variety of therapeutic applications. An asset of using small interfering RNA (siRNA) as therapeutics is their exquisite sequence-specific mechanism of action. It seems possible that the first RNAi therapy that could reach patients would aim at a debilitating eye disease called age-related ma...

Popped eye (blunt trauma leading to penetrating eye injury and lens displacement in the pseudophakic eye).

Blunt trauma to the eye of patients with an artificial intraocular lens may cause globe rupture with all the accompanying sequelae. It must be recognised promptly and dealt with appropriately before urgent referral to ophthalmology.